I. What is Kratom?
Grown in some of the richest lands of the South Asia, a rare tree called as the ‘Kratom’, scientifically named “Mitragyna Speciosa”, grows out leaves that have exceptional attributes.
The leaves of the Kratom tree are considered to be sacred and are used all around the world as natural remedial herbs to treat opiate addiction, relieve pain, lift mood, stimulate immune system and energy from within.
Those mentioned above herbal medicinal attributes of the kratom leafs are just the core and concise ones. Research has discovered many more diversified merits and qualities of Kratom effects that are featured in some of the most important forums and books of the botanical science in detail.
II. Origins of Kratom
The three main countries of the South East Asia that host the natural plantation of the Kratom tree are Thailand, Malaysia, and Indonesia. Indonesia and Thailand additionally feature some more special breeds of the Kratom leaves (based on the sub-regions of these two countries) as illustrated below:
*Sumatra, Borneo, Sunda Isles and Java are the sub-regions of Indonesia. Amongst them the Sunda Isles and Java are Islands. Each breed of the Kratom Leaf found in each of these regions has certain distinctive traits that make them all equally unique when compared to one another.
*Maeng Da is one of the most renowned sub-regions of Thailand that host a truly magnificent and unique breed of the Kratom Leaf.
Although each of the stated region nurture the same plant (of Kratom), each different region produces a unique variety of it. That is because of the different physical, weather and climatic conditions that each region has an ecosystem for each breed of the Kratom as it grows. All of these variations thus collectively and ultimately affect the potency of each strain of the Kratom leaf in an exceptional way before it is ready to be harvested.
The key differences between the types and strains of the Kratom breeds will be explained furthermore in detail.
III. Benefits of Kratom
Kratom is known for some of the most effective and efficient remedial healing attributes by its naturally rich and exceptional alkaloid specifications that make it truly unique and distinctive amongst all other plants in the world.
- Drug withdrawal relief (Transitional maintainer)
- Pain Killer
- Energy Booster
- Mood Enhancer (Euphoric)
- Immune System Stimulant
- Blood sugar stabilizer
Apart from the general medicinal traits of the Kratom as listed above, it also has an abundant supply of potent antioxidant, minerals, and vitamins that make it even more healthy and valuable. Kratom does not contain any element or substance of dangerous nature that can be dangerous to the general health; thus it is safe, definitively.
The pain relieving properties of Kratom are not only effective in general but also in conditions where the pain is much more intense or chronic as compared to other herbal plants with medicinal usefulness. Many individuals have completely altered the way they used to take painkiller medicines in general, in favor of using the naturally rich herbal treatment that the Kratom has to offer instead!
With the ever-growing awareness of the exceptional attributes of the Kratom, it is highly imminent that Kratom would take a commonplace as an alternative to general synthetic pain-relieving pharmaceuticals in the near future, throughout the world. Because ‘Natural is Always Pure and Better.’
Kratom can very effectively aid in diminishing pain from the following conditions:
- Intensive Headache or Migraine
- Minor Injuries (Including, Broken Bones, Scrapes, and Burns)
- Multiple Sclerosis
- Damaged Muscles
- Neck Soreness or Strain
- Chest Pain
- Abdominal Soreness
This was a rather concise outline of the conditions where Kratom can be used as an effective aid. There are yet many other areas as well where the use of Kratom can mitigate and soothe away the pain successfully.
Strains Targeted for Pain Relief
The two of the most powerful Alkaloids present in the Kratom; 7-0H Mitragynine and Mitragynine specifically enhance its ability to alleviate pain actually to a significant extent. Both of these Alkaloids have active opioid delta receptors that mitigate the body’s sensitivity to pain. It is, therefore, important to use those specific strain types of Kratom leaves that have the maximum quantity levels of both of these two featured Alkaloids.
As Alkaloids potency within the content of the leaves varies among the different types and strains of Kratom available, some of the Strains have been tested to be the most powerful ones for the purpose of Pain relief. The most popular ones are:
- Indonesian (Also known as Indo)
- Maeng Da
Ideal Color of Vein
- Moderate to High
Psychological Stimulation (Depression, Anxiety, and Motivation)
The plant of the Kratom has exclusive properties to soothe and refresh the mood psychologically. It contains elements that help in indulging inner peace and sedation through a safe and natural channel. These effects are variable from among the different types of strains available due to the changed level of Alkaloid balancing specifications found in each of them.
In general, each type of strain is well equipped to harness the effects of mood refreshment, euphoric feeling, and motivation. However, some of the strains specifically contain an ideal combination of Alkaloids that amplifies the effects of sedation and stimulation to lift up the feelings even more effectually.
a) Depression Relief
Kratom is indeed beneficial in curtailing depression, but not all of the strains available have significant effects on reducing it, that is because, some strains are better in harnessing sedation, however, they generate temporal effects of motivation and are thus not useful in the long-run.
Some of the most effective Strains of Kratom for reducing and relieving the depression in particular are:
- Maeng Da
- Thailand (*known as Thai)
- Malaysian (*known as Malay)
Ideal Color of Vein
The Green Vein Kratom has also been tested to be effective in alleviating depression successfully. The Green Vein, however, depends more upon the unique chemistry profile of each person’s brain. Therefore, the perception of the intensity of those effects varies from individual to individual.
b) Relieve of Anxiety
The special effects of motivation and vigor generated by the Kratom are uniquely powerful and efficient in minimizing Anxiety.
Here are some of the most actively effectual strains to be used for relieving Anxiety:
Among the strains listed above, Borneo has the most finely potent balance of Alkaloids to overcome restlessness and anxiety even more definitively.
Ideal Color of Vein
Kratom and Drug Withdrawal Relief / Transitional Maintenance
Kratom has great pain relieving and mood-enhancing attributes as discussed above. These traits also make Kratom ideal to be used in conditions where a patient is suffering from the soreness and restlessness of withdrawing from certain drugs that are harmful in nature (like Opium).
Kratom works very effectually in dampening and alleviating the adverse effects of the dangerous drugs and aids in easing the after conditions of those drugs when attempting to combat and overcome them to get back to the usual verve of sobriety.
Recommended Strains to be used for Drug Withdrawal Relief
- Maeng Da
- Indo (Depending upon certain conditions)
Ideal Color of Vein
- Moderate to High
Boosting the Immune System
Kratom has immensely productive immune system boosting capabilities. That is because Kratom leaves are abundant in some of the most qualitative of immune system amplifying Alkaloids, known as the Immunostimulants. These Immunostimulants strengthen the internal defense system of the body (The Immune System).
The overall improvement in the immune system of the body helps in combating with the attacks of the different types of common and severe diseases such as cold, flu or fever. A healthy immune system can repel and in some cases ultimately resist such diseases much more authoritatively as compared to a weaker one.
The four of the most significant alkaloid types of Immunostimulants found in the Kratom leaves are:
Recommended Strains to be used for Boosting Immune System
Ideal Color of Vein
- Green Vein
- Low to Moderate
Memory and Intelligence Enhancement (Nootropic)
Modern research has discovered newer and more likely possibilities about the additional beneficial effects that the Kratom has on enhancing the overall Neurological system capabilities.
Because Kratom is a natural herb, it is free from synthetic medicinal effects that affect Neurological effectiveness permanently and adversely. Kratom improves the overall level of Intelligence focus and memory by cutting down the slack and unnecessary noise in the psychological background while escalating the overall level of concentration definitively more on the ‘focal’ subject matter.
The Kratom aids in adjusting the core attention, enhancing memory and vitalizing alertness through natural means.
Recommended Strains to be used for Enhancing Memory, Intelligence & Energy
- Malay (especially for enhancement in Memory and Intelligence Focus)
- Maeng Da (for improvement in Vigor, Memory and Intelligence Focus)
- Thai (for improvement in Vigor, Memory and Intelligence Focus)
*The variation of the Alkaloid profile in each Strain of Kratom, changes the intensity of the effects it features.
Ideal Color of Vein
- Low to Moderate
IV. Kratom Effects:
Effects of Kratom can be diversified depending on the special mixture and potency of alkaloids present in each of its strains that work cohesively together to generate unique and variable results. Therefore, each strain is effectual and powerful in an exclusive way. Researchers have classified three main categories of the Kratom strains as per the efficiency of effects they can deliver, specifically: Moderate, Sedating and Stimulating.
*Research and Analysis on each individual strain is however not wholly and solely accurate. Strains are selected by their average highest potency values discovered, therefore, no strain fits entirely for just one particular effect out of the three being discussed above, because each Strain of the Kratom is enriched with multiple attributes.
1. Short-term and Long-term Effects of Kratom
Kratom Short-term Effects
With Kratom’s unique composition of chemicals found within its leaves, users have reported varying results when taking Kratom in small dosage. It’s stimulating, and opiate-like results depend heavily on dosage and the user’s body measurement, age, tolerance among other factors.
At the lowest dosage of 1-5 grams per intake, its stimulating effects are more dominant. These effects are felt within 10 minutes and last up to an hour or more. Most Kratom users agree that these results are generally pleasant, but some can also feel a bit uncomfortable. It’s primary stimulating effects are, but not limited to, the following:
– Enhanced social interaction
– Increased libido
– Enhanced energy
– Increased mental and cognitive function
– More balanced appetite
Increasing dosage to medium measurement (5-15 grams) allows the opiate-like effects to be more dominant. These effects last for several hours, more than the stimulating effects when taken in smaller dosage. The said “opiate-like” effects are less intense than opioids and users report of being able to handle it more versus the latter. The known effects of moderate dosage are as follows:
– Calming effects
– Pain relief
– Clearer mental state
– Cough management
– Reduced symptoms of opiate withdrawal
Going for a larger dosage (15 grams or more) leads to extreme sedation and even loss of consciousness in some cases.
Kratom Minor Side Effects
Some users report of feeling some side effects when taking Kratom. Although the list of effects is far from dangerous, it is still important to be aware of its possible occurrences. The minor side effects are listed as follows:
– Excessive sweating
– Stomach problems
– Nausea, Dizziness
– Tiny pupils
– Tremors and jitters (similar to coffee)
It is important to take note that these side effects are nothing but minor, manageable and generally fleeting after a couple of hours. It may seem similar to side effects in Opiate usage, but most users say that Kratom’s side effects are more in passing and can be controlled with responsible usage.
Kratom Long-term Effects
No available established report concludes any damaging effects of Kratom use. Hence, its effects, short-term, and the long-term came from first-hand testimonies and comments of users and individuals who had a fair share of Kratom experiences. Moreover, there has been no available record of deaths related to Kratom use alone, (abusive or not) contrary to media reports. However, as said, some users encounter the following long-term effects in extreme cases:
– Loss of weight; Anorexia
– Darkening of Skin
Some reports also suggest that long-term effects may include Psychosis. Although this rarely happens, in extreme circumstances, and remains invalidated until now. Furthermore, available resources indicate that there are no damaging effects to body organs associated with long-term Kratom usage.
2. Kratom Effects of Different Strains
Effects of Stimulating Strains
This group of strains known as ‘The Stimulators’ possesses’ optimum attributes of focus and energy. The strains this group features are ideal for the individuals who want to retain and enhance their vitality and reduce day-to-day stress and fatigue.
The Primary Kratom breed of Thailand (known as the Thai Kratom) has a great active capability of generating energy and vigor by its highly rich and exceptionally potent profile of Alkaloids. The effects of energy that it renders, however, vary from person to person and they might not be the same for everyone because each has a different biological receptiveness.
Ideal Color of Vein
- Red (Most effective for alleviating Pain as Analgesia)
- White & Green (Effectual when dealing with Depression or stress as an Antidepressant)
The following is an estimated score based on the research done on the Thai Kratom:
- Pain Relief: 7 to 8 / 10
- Stimulation Effectiveness: 9 / 10
- Mood Enhancement: 6 to 9 / 10*
*Efficiency in the effects discussed above depends on some factors and are variable individually from person to person.
Maeng Da Kratom
Maeng Da Kratom is an excellent strain that is known for its marvelously potent and effectual of traits. Maeng Da (being rare in scarce in different variety of vein color availability) works great for both the Stimulation and Pain Relief. It is recommended for those who are looking for a natural pain-killing pacifier with the power to boost up stamina, dynamism, and motivation internally along the way!
- Pain Relief: 7 to 9.5 / 10
- Stimulation effectiveness: 7 to 8.5 / 10
- Mood Enhancement: 7.5 to 9.5 / 10*
*Estimated scores based on a collective research data.
Effects of Sedating Strains
Generally, the Strains specified for Sedation have lower quantities of Alkaloids that Stimulates (i.e. mitragynine that is found in the Maeng Da and Thai strains as discussed earlier).
Sedating strains, however, contains high values of painkilling and mood enhancing Alkaloids such as 7-Hydroxmitragyine that makes these Strains to be more effective specifically for Pain relief, mood enhancement and transitional maintenance when attempting to withdraw from harmful drugs like opium.
Borneo is one of the richest and potent sedating strains of the Kratom. The Borneo strain delivers immensely powerful effects of sedation naturally that are highly effectual for chronic pain relief and stress or anxiety.
The most qualitative trait of the Borneo strain is that even with such a high potency in the effects it harness, it has an extremely low tendency of producing by-product side effects.
Borneo is too a bit uncommon in availability. A pure strain of Borneo can be identified by the exceptionally distinct natural fragrance it possesses.
* Ideal Color of Vein
* Estimated Efficacy
- Pain Relief: 8.5 to 10/10
- Stimulation effectiveness: 1 to 2.5/10
- Mood Enhancement: 8.5 to 10/10
- Bali Kratom
Red Bali is one of the favorite Kratom strains, it grows quicker and larger in size as compared to other strains, thus it is harvested in abundant supplies, making it one of the most inexpensive strains in availability today. Despite being cheap, it is still highly effective in alleviating pain and lifting up the mood naturally.
* Estimated Efficacy
- Pain Relief: 7.5 to 9.5/10
- Stimulation effectiveness: 2.5 to 4 /10
- Mood Enhancement: 7.5 to 9.5/10
*Research has shown that Bali has some limitations to its efficiency when used solitary. However, such limitations can easily be tamed and conquered by using it in a calculated combination with some other strains as well.
The primary Kratom strain of Indonesia (called commonly as the ‘Indo’) is known for its delayed yet compelling and influential effectiveness in contravening pain and reviving the mood.
Researchers believe that the primary reason behind the delayed response of the Indo strain in amplifying its effects is that the toughness of its cell’s wall that acts as a bottleneck.
The Indo Kratom strain generates similar efficacy as compared to the Borneo strain regarding the general research estimates. However, the sophisticated consumers of the Kratom will find the Indo strain to be much more different and unique in itself when used reality because of numerous different factors.
* Estimated Efficacy
- Pain Relief: 8 to 10/10
- Stimulation effectiveness: 2 to 3.5 / 10
- Mood Enhancement: 8.5 to 10 / 10
Effects of Moderate Strains
The Moderate Strains of the Kratom Leafs are immensely popular, they are preferred by a large segment of the market throughout the world. Value Strains provide great merit for money. Although they are not overpoweringly proactive at generating their efficacy instantly, they are still efficient and can deliver multiple effects desired, together smoothly and nicely. These attributes make the Value strains to be perfect for daily (normal) usage for the regular consumers of the Kratom with ease.
Green Malay Kratom
Research tells us that the real breed of the Kratom originated from Malaysia (known to be as the Green Malay Kratom) delivers significant and unique long lasting nootropic effects of ‘precision in focus’, ‘stimulation’, ‘stability’ and ‘enhancement in the overall level of endurance’.
Scientists claim that the main reason behind the persistence of the long-lasting effects amplified by the Malay Kratom is due to the ideal density of its leaf’s cell walls.
* Estimated Efficacy
- Pain Relief: 6 to 8.5/10
- Stimulation effectiveness: 4.5 to 6/10
- Mood Enhancement: 7 to 8.5/10
V. Kratom Vein Color Types: Research & Analysis
It is indeed quite exceptional and exciting to know that despite being the same plant in nature overall, the Kratom available in each vein color type is distinctively different from one another.
All of the three vein color types (Red, Green, and White) provide with a unique array of effects to the consumer because of the variation in their particular Alkaloid profiles (just like it is amongst the different types of strains).
This is because each Vein color type is grown and then developed a particular environmental condition, independently. This also tells us that both the Strain and the Vein color type of a Kratom leaf collectively in aggregate determines the level of potency and the nature of medicinal effect(s) it will generate precisely and efficiently.
Red Vein Kratom
The Red Vein is known for harnessing a powerful sedation with active effects of relieving pain, anxiety, and stress.
This is because the Red Vein tends to be immensely rich in the concentration of 7-Hydroxmitragynine Alkaloids as compared to the other color types of the Kratom leaves available.
One of the finest traits of the Red Vein in contrast to the other Veins (both Green and White) is that it is more compatible with most of its potential consumers (regardless of the common variations of receptiveness found in every individual based on the different levels of brain chemistry).
*Thai amongst the Red Vein color type is one of the most effectual and balanced strain of the Kratom. That is because the Red vein Thai (strain-color) combination features great potency in both; ‘Vigor Enhancement’ and ‘Pain Relief’, both of which are the prime attributes of the Red Vein and Thai Strain respectively.
- Vigor: 3.5 / 10
- Pain Relief: 9.5 / 10
White Vein Kratom
In spite of having a lower concentration of the 7-Hydroynmitragynine Alkaloids, the White vein has immensely dominated and persistence nootropic influences of intelligence focus, alertness, and motivation against stress and depression.
This makes the White Vein Borneo be an ideal alternative to coffee or tea early in the morning for starting the day on with smartness and brilliance.
Amongst all other Vein types, the White Vein spreads out smoother, cleaner and long-lasting effects of stimulation, making them suitable for daily usage.
- Vigor: 9.5 / 10
- Pain Relief: 4 / 10
Green Vein Kratom
The Green Vein is known to be the most moderate vein color type of the Kratom leaf. Green Vein tends to provide an experience of multiple effects at a medium level of strength.
The Green Vein is thus ideal for those who do not want to focus entirely on dedicated effects that the White or Red Vein have to offer (specific effects Stimulation and Sedation respectively).
Overall, the Green Vein provides with modest and neutrally pleasing attributes to its users.
The Green vein type also delivers well-rounded and stable effects of nootropic enhancement and has a higher rate of compatibility amongst most of the individuals, more commonly than the White Vein.
- Vigor: 5 / 10
- Pain Relief: 6 / 10
*All the values of Medicinal Efficacy displayed above are based on average research estimates and may not necessarily reflect perfectly effective values. Some extent of variation can be expected.
VI. Kratom Extracts
The plain leaves of the Kratom are typically quite well balanced and ample in delivering their general medicinal effects, overall. Kratom Extracts, on the other hand, are derived specifically to offer improved potency to counter extreme conditions like ‘chronic pain’ even more effectively.
Kratom Extracts are available in many different variety types. Each variety type of the Kratom Extract has a unique level of potency and an inclination to various distinctive effects based on the Vein, Strain and ultimately the method used in the extraction of the Kratom.
Water Based Kratom Extracts
The most common Kratom Extracts available in the market today are known as the Water Based Extracts. Water Based Extracts of the Kratom are usually obtained through the following procedure:
- Alkaloids extracted from the Kratom leaves are dissolved into water
- The matter is further strained and ground in the form of powder
- The water is thoroughly evaporated
- A brownish material (richer and concentrated in Active Alkaloids than the plain leaf) is left as the residue
The potency of the Water Based Extract is determined derivatively as ‘X’ (i.e. 5X, 20X) as implied on the package to depict the actual amount of the Kratom’s everyday leaf material used in furnishing the mass of the resultant Water Based Extract.
The authenticity of this value can however generally expected to be questioned because many of the vendors mostly tend to label the descriptions with overrated information about their product dishonesty.
- Can be used in combination with the plain leaves (of the Kratom) to increase the overall potency of the effects desired
- Enriched with a higher concentration of active Alkaloids
- Delivers better effects of Stimulation than the base material of a plain leaf
- Little side effects as compared to Resin or other improved extracts (that have an intensified spectrum)
- Can dissolve and liquefy in water
- Not balanced precisely to harness the targeted effects wanted when used independently (i.e. less sedating and pain-relieving effects)
- Needs to be used along with plain leaves to retain stronger and active effects required for pain relief efficiently
- More expensive per potency than the Plain Leaf of the Kratom itself
Kratom Resin is manufactured through a highly specialized procedure in which the strongest concentrate part of the Kratom essence is utilized.
The Kratom leaf concentrate is heated up to be cooked at a certain temperature; it is then dried and condensed into a form of a darkish mixture that is substantially lower in quantity but much greater in the richness of the active Alkaloids it harnesses and the tremendous magnitude of potency that it has to offer.
- Usable quickly
- A wider range of effects unleashed
- Higher potency and concentration power per mass
- Easier to store
- A higher tendency of side effects as compared to the pain leaves
- More costly than the plain leaves
- Higher Sensitivity to temperature (High propensity to melt at even a moderate level of heat)
Kratom’s Tincture is composed by extracting the concentrated essence of the active Alkaloids from the Kratom leaf and then diluting it with the alcohol to achieve a dense liquefied type of solution that is used for a different variety of delivery options (i.e. tropical usage).
If manufactured qualitatively, Kratom Tincture can serve immensely effectual and soothing effects.
- Proactively Responsive
- Usable easily
- Can be Stored Conveniently
- Potency may vary significantly
- Generally more expensive than many other options available
- May not deliver the effects at a wider range of spectrum as it is expected to
Enhanced Kratom, as the name implies is an improved and refined mixture that is finished and perfected to deliver even more actively robust and powerful effects to a greater extent.
The Enhanced Kratom mixture is derived by selecting a very potent extract of the Kratom itself, mixing it with a solution, saturating it into the form of powder and then letting the solution dry.
If prepared meticulously through precision, the resultant mixture solution renders an immensely rich and potent extract of the Kratom.
*The UEI (Ultra Enhanced Indonesia) is the most preferred blend of the Enhanced Kratom Extract.
- A Lower tendency to side effects as compared to the other options available
- Concentrated very well on harnessing greater levels of active Potency
- Very Effective for Pain Relief
- Modified and Customized to be balanced optimally
- May cause some adverse conditions up to a certain extent when ceasing the dose abruptly after using it for a longer time
VII. Alkaloids of Kratom
The main reason behind the variability of effects that each type of Kratom Strain and Vein color depicts uniquely is because of the change in the balance of the Kratom Alkaloids.
Kratom leaf hosts numerous different types of Alkaloids that are naturally enriched in offering distinctive and effective medicinal attributes. The following is a brief list of some of the most popular Alkaloids present in the Kratom along with the precise details about their particular characteristic, concentration, and composition in comparison to their actual mass:
Isomitraphylline: A Primary Stimulant of the Immune System (1% or less concentration of the total composition)
Speciogynine: An Active Muscles Relaxant (6.5 to 7.5%)
Mitragynine: An Effective Mediator of Pain (as an active agonist opiod receptor). Additionally as an Anti-tussive, Anti-diarrheal, Anti-malarial, Adrenergic and a moderate Stimulant (45 to 75%) *minimum recorded concentration of the content material is 12%
Isomitrafoline: As an auxiliary Stimulant of the Immune System (1% or less)
Corynantheidine: As a Subsidiary antagonist opiod receptor (1% or less)
Epicatechin: Effective as an Anti-mutagenic, Anti-leukemic, Anti-oxidant, Anti-viral, Anti-diabetic and Anti-inflammatory. (1% or less) *a significant alkaloid also found in the leaf of the green tea.
Isorhynchophylline: As a mainstream Stimulant of the Immune System (1% or less)
7-Hydroxymitragynine: Primary Analgesic Painkiller (active agonist opiod receptor). Also works effectively as an Anti-tussive and Anti-diarrheal (1.5 to 2.5%)
Isopteropodine: An Active Stimulant of the Immune System (1% or less)
9-Hydroxycorynantheidine: Works efficiently as a secondary Active Analgesic Painkiller (1% or less). *In the presence of the 7-Hydroxymitragynine it aid’s in amplifying the effects of pain relief thoroughly
Ciliaphylline: An efficient anti-tussive analgesic (1% or less)
Mitraphylline: A mainstream muscle relaxant. Additionally, it also works dynamically as an Anti-hypertensive, Anti-amnesic, Vasodilator, Anti-leukemic and a subsidiary Stimulant of the immune system (1% or less)
Ajmalicine: Works primarily as a Cerebrocirculant, Anti-aggregant, and an Anti-adrenergic. Moreover, it also delivers moderate efficacy as a muscle relaxant, sedative and an Anti-convulsant (1% or less)
Corynoxine A: An active Dopamine Stabilizer (1% or less)
Rhynchophylline: A proficient Anti-hypertensive, Anti-inflammatory Vasodilator (1% or less)
Corynoxine B: As a Subsidiary Dopamine Stabilizer it aids in amplifying the effects rendered by Corynoxine A (1% or less)
Speciophylline: A potent Anti-leukemic (1% or less)
Speciociliatine: A Moderate Antagonist opiod receptor (1% or less)
Tetrahydroalstonine: An Efficient Blood sugar stabilizer and an Anti-adrenergic (1% or less)
Mitrafoline: Inactivated – (1% or less)
Akuammigine: Inactivated – (1% or less)
Speciofoline: Inactivated – (1% or less)
Stipulatine: Inactivated – (1% or less)
Mitraversine: Inactivated – (1% or less)
*The values of the concentration percentages as illustrated above are based upon average derivative research data are thus not represented to be perfectly absolute.
The Alkaloids present in the leaves of the Kratom ultimately determine the level of potency and the types of effects they can deliver efficiently.
Many researchers in the past including Dr. Shellard EJ, Takayama H, Lee CM, Becket AH, Raymond Hamet and Philipson JD, in the light of their extensive study and assessments, have concluded that the overall specification profiles of the Alkaloids vary from different types of strains and vein color type greatly.
That is because each strain or vein color type has a unique Alkaloid balance that differentiates on the type and efficacy of the remedial traits they can offer.
For example, the Malaysian strains are enriched in relatively higher levels of the 7-hydroxymitragynine Alkaloid that makes them more powerful in delivering the effects of pain relief.
On the other hand, the Thai strain is has a higher quantity of the Mitragynine Alkaloid that allows it to deliver many other medicinal effects including pain alleviation but at a different level of potency and rate of responsiveness.
Researches and Studies about the types of Alkaloids hosted by the different strains and vein color types of the Kratom plant are ever-evolving and yet to be continued. There is much more to be learned and understood about their magnificent medicinal attributes.
VII. Kratom Dosage
When utilizing the Kratom for its magnificent medicinal traits, dosage is a vitally important aspect for the ones who are expecting specifically targeted effects.
If the dose taken is lower than required, it may bottleneck the remedial capabilities desired. However at the same time, if the dose taken is higher than it is recommended to be consumed then the amount of that excess quantity may lead to some non-hazardous side effects (such as slight nausea and ‘wobbles’) up to a certain extent.
It is therefore imperative that the dosage is taken in optimum quantities so that the real purpose of its utilization is fulfilled both effectively and efficiently.
Average Prescribed Dosage (in Grams)
Low – 1.5 to 2 grams
Medium – 2 to 4.5 grams
*High – 5 to 8 grams
Average Prescribed Dosage (in Teaspoons)
Low – 0.5 to 1 teaspoon
Medium – 1.5 to 2 teaspoons
*High – 2.5 to 3.5 teaspoons
It is important to know that because of the natural variability of potency between the different vein color and strain types of the Kratom’s plant, the estimates of the optimum dosage as prescribed above are not absolute.
This estimation is however merely based upon the collective summary of the research conducted on the historical data and the findings of the study reports.
High dosage (depending on the intensity of the strain and the vein) may generate some minor side effects as per the unique biological receptiveness of the user.